Journal of natural productsAlkyl and Aryl TransferasesDiterpenesMolecular StructurePolyisoprenyl PhosphatesStreptomyces
Discovery and Characterization of a cis-Casbene Diterpene Synthase from Streptomyces paromomycinus.
Xinru Sun, Fang-Ru Li, Qian Yang, Xingming Pan, Hui-Min Xu, Liao-Bin Dong
Published: 202510.1021/acs.jnatprod.5c00870
Abstract
Casbene-type diterpenoids are important bioactive natural products, but all known examples possess exclusively trans-configured double bonds. Here, we report the discovery of SpTS1 from Streptomyces paromomycinus, a diterpene synthase that produces t…
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