Journal of medicinal chemistryMaleHumansDrug ResistanceNeoplasmPhenylthiohydantoin
Preclinical Efficacy of TSL2109 in Prostate Cancer Treatment and Overcoming Enzalutamide Resistance.
Kai Yuan, Wanqi Wang, Chen Tong, Huanaoyu Yang, Weijiao Chen, Xiao-Yu Zhang, Genbei Wang, Guixia Li, Yuanyuan Chen, Xujie Zhuang, Wenjian Min, Haiping Hao, Yibei Xiao, Xiaohui Ma, Peng Yang
Published: 202510.1021/acs.jmedchem.5c03245
Abstract
Prostate cancer (PCa) is a highly prevalent and aggressive malignancy that poses a serious threat to men's health globally. Current treatments for PCa largely rely on hormone therapy; however, the development of drug resistance significantly diminish…
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