Journal of medicinal chemistryFluorescent DyesChemical and Drug Induced Liver InjuryEsterasesAnimalsMice
Prominent Imaging for Differentiating Severity of Drug-Induced Liver Injury by an Esterase Activatable Near-Infrared Fluorescent Probe.
Hong-Zhen Wang, Yi-Ran Shu, Ying Luo, Dong-Mei Xi, Tian-Bing Ren, Lin Yuan, Xiao-Peng Fan
Published: 202610.1021/acs.jmedchem.5c03044
Abstract
Efficient imaging and differentiation of the severity of drug-induced liver injury (DILI) under diabetic conditions are crucial for preclinical drug safety evaluation. However, due to the absence of robust and distinctive parameters, most of the repo…
Preview only. Read the full abstract at the source