Journal of medicinal chemistry
An Azoreductase-Activated Self-monitoring Prodrug for Chemiluminescence Imaging and Safe Chemotherapy Breast Cancer.
Tianrong Yang, Ye Wang, Nan Gao, Xiaosong Zhu, Sanjun Zhao, Baoqu Wang, Min Xu
Published: 202610.1021/acs.jmedchem.5c02922
Abstract
Theranostic prodrugs predominantly rely on fluorogenic responses to convey diagnostic signals during chemotherapeutic activation. While chemiluminescence (CL) detection offers superior signal-to-noise ratios over fluorescence, the utilization of Scha…
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