Journal of medicinal chemistry
Quinoline/Naphthalene-Embedded PSMA Probes for Precise PET Imaging with Minimized Undesired Retention.
Zhexin He, Hongwu Liu, Qian Yu, Shihan Chen, Jiahui Sun, Yiqing Chi, Jieying Huang, Ben Li, Mingxin Zhang, Yesen Li, Rongqiang Zhuang, Xianzhong Zhang, Guangjie Yang, Zhide Guo
Published: 202610.1021/acs.jmedchem.5c02804
Abstract
Accumulation in nontarget tissues, particularly the salivary glands, remains a major challenge for prostate-specific membrane antigen (PSMA)-targeted radiotherapeutics, narrowing the theranostic window. In this work, we developed quinoline/naphthalen…
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