Journal of medicinal chemistryHumansNeoplasmsProto-Oncogene Proteins c-mycAntineoplastic AgentsAnimals
Alternative Strategies of Reducing MYC Expression for the Treatment of Cancers.
Huijuan Chen, Jingfeng Song, Yihang Wang, Zhijin Peng, Hongyu Zeng, Hu Zhou, Wenbin Shang, Yihua Chen
Published: 202610.1021/acs.jmedchem.5c02684
Abstract
MYC is a master oncogene regulating cell proliferation, differentiation, cell cycle, metabolism, and apoptosis, which is implicated in nearly 70% of human cancers. Targeting MYC dysregulation represents a promising therapeutical strategy for cancer t…
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