Journal of medicinal chemistryHumansNuclear Receptor Coactivator 3CREB-Binding ProteinPeptidesp300-CBP Transcription Factors
Targeted Inhibition of CBP/p300-NCOA3 Interactions with an α-Methylated Peptide.
Aurora Silvestri, Judit Osz, Alexis Jouin, Valentin Bauer, Sandra Chalhoub, Vladimir Torbeev, Natacha Rochel
Published: 202610.1021/acs.jmedchem.5c02636
Abstract
The CREB-binding protein (CBP) and its paralogue p300 are cellular integrators of various signaling pathways involved in various physiological functions. Together with NCOA proteins, they act as coactivators of nuclear receptors. CBP/p300 and NCOA3 a…
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