Journal of medicinal chemistryHumansRutheniumAnimalsAntineoplastic AgentsIsoquinolines
Isoquinoline-Derived Half-Sandwich Ru(II) Arene Complex Potentiates Antitumor Chemoimmunotherapeutic Response.
Jing Yang, Ya-Qian Shi, Song He, Meng-Fan Zhu, Tian-Xia Wu, Liang-Mei Yang, Wei Zhang, Feng-Yang Wang, Yuan Lu, Hong Liang, Ke-Bin Huang
Published: 202510.1021/acs.jmedchem.5c02405
Abstract
Metal-based chemoimmunotherapy has recently attracted considerable interest for its ability to stimulate tumor-specific immunity beyond direct cytotoxic effects. These immunostimulatory outcomes are commonly mediated through immunogenic cell death (I…
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