Journal of medicinal chemistryErbB ReceptorsAnimalsHumansMiceCell Line
Precision Chemoradiotherapy via EGFR Targeting with Radiotherapy-Activated Drug Conjugates.
Shanmeng Lin, Jinyan Luo, Jinying Yang, Kui Tan, Qi Xing, Shiling Zhang, Quan Gao, Jin Geng
Published: 202510.1021/acs.jmedchem.5c01716
Abstract
The strategy of concurrent chemoradiotherapy (CCRT) has been developed, aiming to leverage the benefits of chemotherapy and radiotherapy while mitigating their respective limitations. In this study, we innovatively employed an azobenzene structure as…
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