Journal of chemical theory and computationNeural NetworksComputerAntibodiesDiffusionAmino Acid Sequence
AbEgDiffuser: Antibody Sequence-Structure Codesign with Equivariant Graph Neural Networks and Diffusion Models.
Yibo Zhu, Xiumin Shi, Jingjuan Zhang, Weizhong Sun, Lu Wang
Published: 202510.1021/acs.jctc.5c00990
Abstract
Antibodies are crucial immune proteins with high antigen specificity. Conventional antibody engineering is time-consuming and inefficient, whereas deep learning-driven specific antibody design offers an innovative avenue for drug discovery. In this w…
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