Journal of chemical information and modeling
Combined Modeling Approaches for Assessing Sodium-Iodide Symporter Inhibition.
Julia Kandler, Ayse Sıla Kantarçeken, Aljoša Smajić, Gerhard F Ecker
Published: 202610.1021/acs.jcim.5c02855
Abstract
The sodium-iodide symporter (NIS, SLC5A5) plays a crucial role in thyroid hormone synthesis. Especially during brain development, correct thyroid signaling is of critical importance. Hence, inhibition of this transporter can lead to neurodevelopmenta…
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