Journal of chemical information and modeling
Computational Exploration of the Molecular Mechanism of Epigallocatechin Gallate against TDP-43 Aggregation.
Wenjuan Yi, Zhengdong Xu, Dushuo Feng, Lulu Guan, Jiaxing Tang, Yu Zou
Published: 202610.1021/acs.jcim.5c02616
Abstract
Cytoplasmic accumulation of the transactive response deoxyribonucleic acid (DNA)-binding protein of 43 kDa (TDP-43) aggregates represents the primary pathological hallmark of TDP-43 proteinopathies including amyotrophic lateral sclerosis (ALS) and ch…
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