Journal of chemical information and modelingDeep LearningDrug DiscoveryProtein BindingPharmaceutical Preparations
MambaTransDTA: A Hybrid Mamba-Transformer Architecture for Accurate Drug-Target Binding Affinity Prediction.
Xinpo Lou, Jianxiu Cai, Qidong Liu, Shirley W I Siu
Published: 202610.1021/acs.jcim.5c02361
Abstract
In recent years, deep learning techniques have made significant advances in drug-target affinity (DTA) prediction. However, existing models still have considerable room for improvement in prediction accuracy, robustness, and generalization ability. T…
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