Journal of chemical information and modelingPeptidesSARS-CoV-2Spike GlycoproteinCoronavirusHumans
Targeting SARS-CoV-2 Receptor Binding Domain and Main Protease with D-Peptides.
Laiyi Feng, Jingjia Liu, Chunmei Li, Qian Wang, Luhua Lai, Changsheng Zhang
Published: 202510.1021/acs.jcim.5c01839
Abstract
D-peptide binders are promising drug candidates that may offer better binding specificity and improved metabolic stability than canonical peptide drugs. However, there is a lack of efficient computational methods for the de novo design of D-peptide b…
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