Journal of agricultural and food chemistry
Protocatechuic Acid, a Gut-Derived Dietary Metabolite, Attenuates Endothelial Dysfunction via GPER-Mediated NO Signaling.
Seung Yeon Lee, Jae Won Kim, Anh Thi Ngoc Bui, Jeonghwan Maeng, Gi Ho Lee, Wooyeon Jo, Sang Ki Lee, Hwi-Yeol Yun, Eun Hee Han, Hye Gwang Jeong
Published: 202610.1021/acs.jafc.5c15753
Abstract
Protocatechuic acid (PCA), a gut-derived metabolite of dietary polyphenols, exhibits endothelial protective properties, yet its underlying mechanisms remain unclear. In this study, we investigated the molecular pathways by which PCA attenuates endoth…
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