Journal of agricultural and food chemistryAnimalsDietHigh-FatObesityMice
Ganoderma lucidum Polysaccharides Alleviate High-Fat Diet-Induced Obesity by Promoting Lipolysis and Inhibiting Inflammation through Lactobacillus johnsonii-Butyrate Axis.
Tingting Sang, Ting Xu, Cheng Chen, Jianjun Wu, Chengjie Zhou, Fenfen Li, Lanxi Xu, Shuyan Liu, Meiyu Wang, Yani Zhang, Daozong Xia, Lisheng Chu
Published: 202610.1021/acs.jafc.5c12282
Abstract
Ganoderma lucidum polysaccharides (GLPs) exert antiobesity effects that are linked to gut-microbiota modulation, yet the underlying mechanisms remain elusive. Here, we show that GLPs raise the fecal butyrate level, which in turn inhibits high-fat die…
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