Journal of agricultural and food chemistryAnimalsSirtuin 1NF-kappa BDiabetic NephropathiesMice
Lupiwighteone Ameliorates Diabetic Nephropathy-Induced Renal Fibrosis via SIRT1/NF-κB Signaling Pathway-Mediated Inflammatory Response.
Hao Yang, Hong Pan, Zhigang Chen, Yujie Wang, Wenjie Jiang, Hufeng Fang, Kun Yan, Jie Ren, Lidan Tang, Shan Xu
Published: 202510.1021/acs.jafc.5c10001
Abstract
Diabetic nephropathy (DN) is a severe diabetic complication leading to end-stage renal disease (ESRD), driven by inflammation and fibrosis. Lupiwighteone (Lup), an isoflavone with documented anti-inflammatory and anticancer activities, remains unchar…
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