Journal of agricultural and food chemistryUnfolded Protein ResponseAnimalsUrsolic AcidImmunityInnate
Ursolic Acid Activates Mitochondrial Unfolded Protein Response to Enhance Innate Immunity via Transcription Factor ATFS-1/ATF5.
Jun Xiong, Xiaocong Li, Fangfang Mao, Nengyue Wang, Fang Liu, Yi Xiao
Published: 202510.1021/acs.jafc.5c09928
Abstract
Ursolic acid (UA), a pentacyclic triterpenoid found in various plants, exhibits diverse biological activities. The mitochondrial unfolded protein response (UPRmt) acts as a pivotal regulator in orchestrating innate immune responses. However, it remai…
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