Journal of agricultural and food chemistryAnimalsInsecticidesDrosophila melanogasterDopa DecarboxylaseMolecular Docking Simulation
Validation of Insect Dopa Decarboxylase as a Potential Insecticide Target and Discovery of Selective Lead Compounds.
Xue Hu, Yi Ding, Huan Liu, Zihan Pang, Mingjia Gao, Tian Liu
Published: 202510.1021/acs.jafc.5c09908
Abstract
Dopa decarboxylase (DDC) is a key rate-limiting enzyme involved in cuticle tanning in insects, catalyzing the conversion of l-dopa to dopamine. Given its essential role in insect survival, DDC represents a potential target for pest control. In this s…
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