Journal of agricultural and food chemistryFlavanonesMetabolic EngineeringGlycosyltransferasesEscherichia coliArabidopsis
Engineering Efficient Biosynthesis of Baicalein-7-O-xyloside in Escherichia coli via Glycosyltransferase Evolution and Metabolic Pathway Optimization.
Xiaomeng Zhang, Zhipeng Qi, Guosheng Xiao
Published: 202510.1021/acs.jafc.5c07786
Abstract
Glycosylation expands natural product diversity. Baicalein, a bioactive compound from Scutellaria baicalensis, suffers from poor solubility and bioavailability. Hence, we engineered a novel baicalein xyloside using Arabidopsis thaliana glycosyltransf…
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