Journal of agricultural and food chemistryMetabolic EngineeringYarrowiaPolyketidesSalicylatesFungal Proteins
Systematic Metabolic Engineering of Oleaginous Yeast Yarrowia lipolytica for Efficient Synthesis of Polyketide 6-Methylsalicylic Acid.
Wenping Wei, Mengfan Li, Gaopan Cai, Jiayun Xu, Ping Zhang, Tao Qian, Xiaochuan Chen, Haiyang Su, Yihui Zhu, Xiaohe Chu, Bang-Ce Ye
Published: 202510.1021/acs.jafc.5c07541
Abstract
The polyketides 6-methylsalicylic acid (6-MSA) exhibits good resistance to plant pathogens and considerable application potential. However, conventional methods, such as plant extraction, have limited its industrialization and green synthesis. Microb…
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