Journal of agricultural and food chemistryAnimalsToll-Like Receptor 4LipopolysaccharidesNLR FamilyPyrin Domain-Containing 3 Protein
Sinensetin Ameliorates Lipopolysaccharide-Induced Liver Injury by Targeting the TLR4/NF-κB/NLRP3 Pathway and Related Gut-Liver Axis Dysfunction in Mice.
Zhuoqun Meng, Qin Zhang, Ranran Zhang, Guirong Liu, Wenliang Xiang, Yang He, Qing Zhang, Jie Tang
Published: 202510.1021/acs.jafc.5c07080
Abstract
Sinensetin is a multimethoxy flavonoid that exhibits biological activities and can reduce lipopolysaccharide (LPS) induced liver injury, but it is unknown if it acts via the gut-liver axis. In the study, a mouse model was established to assess the po…
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