Inorganic chemistry
Direct Arylation of Unactivated Arenes Using Earth-Abundant Iron/Tetra-Aza Macrocyclic Complexes.
Tahmina Afroz, David M Freire, Timothy J Hubin, Kayla N Green
Published: 202610.1021/acs.inorgchem.5c04793
Abstract
Biaryl motifs are central in pharmaceutical drug design, yet conventional synthesis via palladium-catalyzed cross-coupling poses increasing sustainability and cost concerns. The study presented herein explores a greener alternative to palladium using…
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