Chemical research in toxicologyHumansTyrosineTandem Mass SpectrometryHemoglobinsBreast Neoplasms
Chlorotyrosine and Dichlorotyrosine in Hemoglobin of Breast Cancer Patients Analyzed by Liquid Chromatography Tandem Mass Spectrometry.
Wei-Ru Pan, Ren-Jye Lee, Chi-Wen Tu, Hauh-Jyun Candy Chen
Published: 202610.1021/acs.chemrestox.5c00436
Abstract
3-Chlorotyrosine, a product of hypochlorous-acid-induced protein tyrosine chlorination in inflamed tissues, has been considered a marker of oxidative inflammation in vivo. However, it has been proposed that the dichlorination of tyrosine might serve…
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