Chemical research in toxicology
The Bladder as a Target for PCB Toxicity: Evidence from PCB Levels, Phase I Metabolite Levels, and Cytochrome P450 Expression Following Developmental Exposure to a Human-Relevant PCB Mixture in Mice.
Hui Wang, Elaine A Schumacher, Audrey Spiegelhoff, Conner L Kennedy, Monica M Ridlon, Rachel F Marek, Kimberly P Keil Stietz, Hans-Joachim Lehmler
Published: 202610.1021/acs.chemrestox.5c00431
Abstract
Lower urinary tract dysfunction is multifactorial, yet the role of environmental exposure remains poorly investigated. Developmental exposure to polychlorinated biphenyls (PCBs) has been linked to altered voiding in mice; however, the disposition of…
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