Chemical research in toxicologyHorseradish PeroxidasePeptidesHumansHydrogen PeroxideMolecular Structure
Applicability Domain of Peroxidase Peptide Reactivity Assay (PPRA): Chemical Structure Analysis and Grouping of Peptide Depletion Patterns.
Gang Yan, Petra S Kern, Kim Ellingson, Mengying Zhang, G Frank Gerberick, Isabelle Lee, Cindy Ryan, Isabella Schember
Published: 202510.1021/acs.chemrestox.5c00321
Abstract
Skin sensitization is a critical endpoint in human safety risk assessment of chemicals. Risk assessment approaches have evolved, and the field has seen a shift toward adopting new approach methods (NAMs) instead of relying solely on animal or human d…
Preview only. Read the full abstract at the source