Biomacromolecules
Crowding-Induced Liquid-Liquid Phase Separation in the ATP-Binding ACC1-13K8 Peptide Leads to a Distinct Amyloid Variant.
Robert Dec, Wojciech Dzwolak, Roland Winter
Published: 202610.1021/acs.biomac.5c02213
Abstract
Liquid-liquid phase separation (LLPS) is involved in both the self-assembly of vital cellular organelles and the disease-associated protein misfolding, where LLPS precedes a liquid-solid phase transition (LSPT) leading to amyloid aggregates. Chimeric…
Preview only. Read the full abstract at the source