BiomacromoleculesFibroinsAnimalsHydrogelsRegenerationMice
Irisin-Loaded Physically Cross-linked Silk Fibroin Hydrogel Promotes Muscle Fiber Regeneration in Volumetric Muscle Loss.
Yanzhu Shi, Yilin Zhang, Yuwei Zhang, Linhao Li, Lizhen Wang, Yubo Fan
Published: 202510.1021/acs.biomac.5c01700
Abstract
Volumetric muscle loss (VML), often resulting in irreversible motor impairment, poses a significant challenge for musculoskeletal repair. This study introduces a biodegradable silk fibroin (SF) hydrogel as an irisin delivery system for VML treatment.…
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