Conformation-Activity Relationship of Amphiphilic l-Alanine and l-Lysine Block Copolymers: From Dynamic Ice-Inhibition Mechanisms to Rational Molecular Design.

We establish a direct relationship between conformational flexibility and ice-inhibition activity in an amphiphilic block copolymer of l-alanine and l-lysine (PA-b-PK), revealing that rationally restricting conformational variation is a key strategy…

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