BiomacromoleculesPeptoidsCollagenHumansPeptidesProtein Binding
Modulating Refolding and Collagen Binding of Collagen Hybridizing Peptides through Peptoid Incorporation.
Pahweenvaj Ratnatilaka Na Bhuket, Han Wu, Sheri L Holmen, S Michael Yu
Published: 202610.1021/acs.biomac.5c01075
Abstract
Collagen hybridizing peptides (CHPs) selectively bind denatured collagens (dColl), offering a powerful platform for diagnostics and targeted drug delivery. However, the rapid self-trimerization of GPO-derived CHPs (O = hydroxyproline) limits their ap…
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