Bioconjugate chemistry
Development and Evaluation of [68Ga]Ga-FA-PSMA: A Folic Acid-Conjugated PSMA-Targeting Radiotracer for Enhanced PET Imaging of Prostate Cancer.
Yukai Zhang, Qingyu Zhang, Jingye Li, Bowu Zhang, Jianjun Liu, Cheng Wang
Published: 202610.1021/acs.bioconjchem.5c00597
Abstract
Prostate-specific membrane antigen (PSMA) is a critical biomarker for prostate cancer. While current radiotracers like [68Ga]Ga-PSMA-11 are clinically useful, enhancing tumor uptake and contrast remains a goal. Capitalizing on PSMA's enzymatic hydrol…
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