Bioconjugate chemistrySingle-Domain AntibodiesHumansImmunotherapyHepatitis B VaccinesPeptides
Chemoenzymatic Synthesis of Nanobody-Peptide Conjugates Capable of Harnessing HBV Vaccine-Induced Antibodies for Cancer Immunotherapy.
Haofei Hong, Zijiang Zhang, Zheng Wang, Zongqin Zhang, Linpei Zhang, Zhimeng Wu
Published: 202610.1021/acs.bioconjchem.5c00413
Abstract
Redirecting endogenous antibodies toward tumor cells through rationally designed antibody-recruiting molecules (ARMs) has emerged as a promising strategy in cancer immunotherapy. However, current ARMs face inherent limitations, as they primarily depe…
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