Bioconjugate chemistryInosineRNA EditingHumansAdenosineGene Expression Profiling
Propiolates-Based Selective Labeling and Affinity Capture Enables High-Fidelity Transcriptome-Wide Profiling of A-to-I RNA Editing.
Jian-Feng Qin, Tong-Meng Yan, Chen Huang, Ying-Wei Wang, Yu Pan, Hao Shi, Pei-Jie Zhu, Xiao Yang, Zhi-Hong Jiang
Published: 202510.1021/acs.bioconjchem.5c00300
Abstract
Adenosine-to-inosine (A-to-I) RNA editing is a critical post-transcriptional modification that regulates various biological processes and has been implicated in neurological diseases, cancer, and autoimmune diseases. However, current methods for dete…
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