Hydrophobic Regulation of Ion-Exchange Cellulose Microspheres Activating an "Ionic Anchoring-Hydrophobic Locking" Mechanism for Enhanced Protein Chromatographic Resolution.

High separation resolution is essential for ion-exchange chromatography to achieve purification of proteins with similar net surface charge within a limited separation window. Herein, the hydrophobic-regulated design concept was proposed to enhance t…

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