Analytical chemistryHeminLuminescent MeasurementsDNAHybridomasAnimals
Hemin-DNA Switch-Assisted Microfluidic Chemiluminescence Immunoimaging for Rapid and Quantitative Screening of Specific Hybridomas.
Wencheng Xiao, Hang Ao, Nilin Wu, Jun Sun, Wenrui Hu, Yunlong Chen, Jie Wu, Huangxian Ju
Published: 202610.1021/acs.analchem.5c07461
Abstract
Highly sensitive detection of cell secretions at the single-cell level is critical for efficient cell screening and monoclonal antibody (mAb) production. Herein, we present a highly sensitive microfluidic chemiluminescence immunoimaging (μCLII) metho…
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