Analytical chemistry
Unraveling Chiral Recognition for Ofloxacin Enantiomers: An IMS-MS Study Enabled by Noncovalent Complexation and Theoretical Modeling.
Xue Yang, Yao Pan, NaiSheng Wu, Huiqing Ding, Fangling Wu, Li Ding, Chuan-Fan Ding
Published: 202610.1021/acs.analchem.5c07410
Abstract
The precise analysis of chiral drugs is crucial for elucidating their stereoselective pharmacological effects. As a commonly used fluoroquinolone antibiotic, ofloxacin (OFLX) exhibits different pharmacodynamics between its R- and S-OFLX, highlighting…
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