Analytical chemistryAmyloid beta-PeptidesHydrophobic and Hydrophilic InteractionsFluorescent DyesStilbenesHumans
Amphiphilic Tetraphenylethylene Derivative with Hydrophobic-Hydrophilic Complementarity to Amyloid Oligomers for in Situ Imaging and Modulation of Membrane-Disruptive Neurotoxicity.
Jian Chen, Xiongwei Tang, Yichen Hu, Huixia Feng, Guanxin Zhang, Deqing Zhang, Yanyan Huang, Rui Zhao
Published: 202610.1021/acs.analchem.5c07117
Abstract
Amyloid oligomers are key targets for probing and regulating neuronal activities and disorder, whose recognition and detection, however, remain challenging due to their transient and heterogeneous nature. In this work, inspired by the membrane intera…
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