Analytical chemistrySingle-Cell AnalysisProteomicsHumansSepharoseMass Spectrometry
Temperature-Responsive Agarose-Based Digital Microfluidics: An In-Chip Sample Preparation To Mass Spectrometry Analysis for Trace Cells and Single-Cell Proteomics.
Ling Yan, Jiacheng Fang, Huimin Zhang, Yali Lin, Dan Li, Yingyan Zhou, Lin Zhu, Zhi Zhu, Pengyuan Yang, Zongwei Cai
Published: 202610.1021/acs.analchem.5c06267
Abstract
Mass spectrometry (MS)-based single- and trace-cell proteomics provides critical insights into cellular phenotypes, but widespread use is limited by the cost and complexity of advanced MS systems. We present a cost-effective, accessible workflow comp…
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