Analytical chemistryUltraviolet RaysSpectrophotometryInfraredGasesNucleotides
Cryogenic Gas-Phase Infrared Ion Spectroscopy of Ultraviolet-Induced Nucleotide Photoproducts.
Gurpur Rakesh D Prabhu, Michael Götze, Kim Greis, América Y Torres-Boy, Marc Safferthal, Dominika Strzelecka, Carla Kirschbaum, Nimish D Deshpande, Niklas Geue, Gerard Meijer, Gert von Helden, Kevin Pagel
Published: 202510.1021/acs.analchem.5c05815
Abstract
Ultraviolet (UV) exposure induces cross-linked pyrimidine dimers in nucleic acids, primarily forming cyclobutane pyrimidine dimers and 6-4 pyrimidine-pyrimidone adducts. These photoproducts exist in multiple isomeric forms, and various dimeric combin…
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