Analytical chemistryHumansSurvivinApoptosisAutophagyAptamers
Multiplex Aptamer-Guided DNA Nanosuppressors for Quantitative Modulation of Autophagy-Survivin Crosstalk and Imaging-Guided Apoptosis Induction.
Zijie Tang, Lina Zhu, Jiani Ding, Zhi-Ling Song, Xiliang Luo
Published: 202510.1021/acs.analchem.5c05754
Abstract
Survivin, a critical inhibitor-of-apoptosis protein frequently overexpressed in cancer, represents a promising therapeutic target, yet its efficacy is confounded by the intricate interplay with autophagy. To quantitatively dissect this interplay, we…
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