Analytical chemistry
The Simplest Method Yet for Ultrafast Desalting of Proteins and Oligonucleotides in Native Mass Spectrometry.
Edvaldo V S Maciel, Jonathan Eisert, Christian Hake, Alexander Schießer, Frederik Lermyte
Published: 202610.1021/acs.analchem.5c05700
Abstract
Native mass spectrometry can provide information on the structural context and interactions of proteoforms and other biomolecules. Despite its strengths, the incompatibility of this method with nonvolatile salts present in conventional buffers limits…
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