Analytical chemistry
IsoPS-DIA: Dual Functionality of Absolute Targeted Quantification and Global Proteome Profiling.
Hsin-Ju Chan, Huan-Chi Chiu, Li-Yu Chen, Chi-Ting Lai, Chia-Yen Wang, Shr-Uen Lin, Sung-Liang Yu, Yu-Ju Chen
Published: 202610.1021/acs.analchem.5c05651
Abstract
Current gene testing reveals only the mutation status yet lacks protein expression of the actual drug target. A comprehensive evaluation requires methods that integrate the absolute quantification of mutant proteins with global profiling of downstrea…
Preview only. Read the full abstract at the source