Analytical chemistryCatecholsHumansHeLa CellsProteomeMolecular Docking Simulation
Nonmodified Strategy Enabled Proteome-Wide Mapping of Catechol Derivatives Interactome.
Zichun Qiao, Xiaozhe Zhang, He Wang, Yichu Shan, Xiao Li, Chuhan Cao, Zhen Liang, Yukui Zhang, Bo Jiang, Lihua Zhang
Published: 202610.1021/acs.analchem.5c05567
Abstract
Profiling the interactome of catechol derivatives plays a key role in revealing their pharmacology. Existing approaches for target identification generally rely on either the modification of ligands or significant perturbation of protein properties,…
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