Analytical chemistryCross-Linking ReagentsClick ChemistrySuccinimidesHumansMass Spectrometry
Clickable Multitargeting Cross-Linkers Based on SuFEx for In Vivo Cross-Linking Mass Spectrometry.
Yanhong Hao, Moran Chen, Xiao Huang, Hui Xu, Ming Gao, Pengfei Wu, Qingtao Meng, Suming Chen
Published: 202610.1021/acs.analchem.5c05561
Abstract
Cross-linking mass spectrometry (XL-MS) is a powerful technique to study protein structures and protein-protein interactions. The coverage of amino acids determines the depth of the XL-MS analysis and accuracy of the structural resolution. In this wo…
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