Analytical chemistrybeta-LactamasesHumansBacterial ProteinsKlebsiella pneumoniaeBiosensing Techniques
Culture- and PCR-Free Femtomolar Detection of Antibiotic Resistance Genes in Clinical Urine via Cascaded Molecular Machines and Electrokinetic Enrichment.
Hanren Chen, Bihong Diao, Xiumei Hu, Jiayi Xiao, Lihong Liu
Published: 202510.1021/acs.analchem.5c05344
Abstract
The rapid detection of antibiotic resistance genes (ARGs) is crucial for guiding precise antibiotic therapy and preventing the spread of resistant pathogens. Here, we report a triple-signal amplified biosensor that integrates cascaded molecular machi…
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