Analytical chemistryHumansReceptor Protein-Tyrosine KinasesProtein MultimerizationPhosphorylationEnzyme Activation
A Chemically Inducible Multimerization System for Tunable and Background-Free RTK Activation.
Yuanmin Zheng, Jinyu Fei, Abhirup Chakrabarti, Ruobo Zhou
Published: 202610.1021/acs.analchem.5c05190
Abstract
Receptor tyrosine kinases (RTKs) are key regulators of diverse cellular processes, including differentiation, migration, proliferation, survival, and intracellular communications by transducing extracellular cues into intracellular responses. Upon ol…
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