Analytical chemistryHumansRNALong NoncodingNucleic Acid HybridizationManganese Compounds
Sensitive Imaging of Intracellular Long Noncoding RNAs In Situ in Living Cells Based on Synergistic Dual Hybridization Chain Reaction.
Yanfei Zhang, Yutian Lei, Jun Chen, Si-Yang Liu, Xing Han, Zong Dai
Published: 202510.1021/acs.analchem.5c03947
Abstract
Sensitive and specific imaging of long noncoding RNAs (lncRNAs) in situ in living cells is severely challenged by their lengthy sequences and trace amount. Enzyme-free isothermal nucleic acid amplification methods, particularly hybridization chain re…
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