Molecular therapy : the journal of the American Society of Gene Therapy
Prosaposin is a Dual-Action Therapeutic Target for Vascular Stabilization and Neuroprotection.
Jianhao Bai, Sijie Li, Aiting Wang, Boqian Wang, Zhongqi Wan, Jiao Jiao Li, Yinghong Zhou, RenBing Jia, Haiying Jin, Peng Gao, Xianting Ding
Published: 202610.1016/j.ymthe.2026.01.015
Abstract
The disruption of vascular homeostasis is a key pathological feature of fundus abnormal vascular diseases, including wet age-related macular degeneration, diabetic macular edema, and retinal vein occlusion. While anti-vascular endothelial growth fact…
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