Metabolic engineering
Genome minimization of a Burkholderia bacterial host.
Bruno S Paulo, Sean B Romanowski, Adjo E Kadjo, Vitor B Lourenzon, Alessandra S Eustáquio
Published: 202610.1016/j.ymben.2026.01.008
Abstract
Genome minimization, including the deletion of endogenous gene clusters that encode natural products, is a common strategy to improve the yield of heterologous products. We have been interested in developing Burkholderia sp. FERM BP-3421 as an altern…
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