Metabolic engineering
Machine learning-driven optimization of metabolic balance for β-carotene production.
Weiming Tu, Jiabao Xu, Yongshuo Ma, Constantinos Katsimpouras, Gregory Stephanopoulos
Published: 202510.1016/j.ymben.2025.12.002
Abstract
Balancing metabolic pathways is critical for engineering microbial platforms to efficiently and robustly synthesize value-added bioproducts. In the oleaginous yeast Yarrowia lipolytica engineered for β-carotene production, lipid synthesis supports ca…
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